Dosing and Administration
Qudexy® XR is carefully formulated with patient adherence in mind.
Open up possibilities for your patients with dosing flexibility:1
- Taken once daily
- Work with your patients to choose the time of day they will take Qudexy® XR
- Can be taken with or without food
† Recommended dose for migraine prophylaxis: 100 mg once daily.
Capsules shown are not exact size or color. Proportions are to scale.
Sprinkle Administration Option
Qudexy® XR is the only extended-release topiramate formulation approved for sprinkle administration.
All strengths of Qudexy® XR capsules may be opened and the contents sprinkled onto a spoonful of soft food. Sprinkle administration is bioequivalent to the intact capsule.1
Instructions for patients:
- Swallow mixture immediately
- Do not store for later use
- Do not chew or crush
- Drink fluids right after eating the mixture to make sure it is all swallowed
For illustrative purposes only. Capsule shown is not exact size or color.
Dosing and Titration1
|Adults and adolescents 12 years of age and older||Increase dose weekly to an effective dose by increments of
||100 mg once daily|
Monotherapy: Partial-Onset or Primary Generalized Tonic-Clonic Seizures
|Adults and pediatric patients 10 years and older||Increase dose weekly by increments of
||400 mg once daily|
|Pediatric patients 2 to less than 10 years||25 mg orally once daily at nighttime for the first week||Titrate the dosage over 5 to 7 weeks||Once-daily doses based on weight*|
|Adults with partial-onset seizures or Lennox-Gastaut syndrome (LGS)||25 mg to
||Increase dose weekly by increments of
|Adults with primary generalized tonic-clonic seizures||Increase dose weekly to an effective dose by increments of
|Pediatric patients 2 years and older with partial-onset seizures, primary generalized tonic-clonic seizures or LGS||Increase dosage at 1 or 2 week intervals by increments of
*See Table 2 in the Qudexy® XR Prescribing Information.
1. Qudexy® XR [package insert]. Maple Grove, MN: Upsher-Smith Laboratories, Inc.; March 2017.